diff --git a/.github/.OwlBot.lock.yaml b/.github/.OwlBot.lock.yaml
index 649877dc4..a9fcd07cc 100644
--- a/.github/.OwlBot.lock.yaml
+++ b/.github/.OwlBot.lock.yaml
@@ -1,3 +1,3 @@
 docker:
   image: gcr.io/repo-automation-bots/owlbot-python:latest
-  digest: sha256:50e35228649c47b6ca82aa0be3ff9eb2afce51c82b66c4a03fe4afeb5ff6c0fc
+  digest: sha256:9743664022bd63a8084be67f144898314c7ca12f0a03e422ac17c733c129d803
diff --git a/docs/conf.py b/docs/conf.py
index cb347160d..09f7ea414 100644
--- a/docs/conf.py
+++ b/docs/conf.py
@@ -110,6 +110,7 @@
 # directories to ignore when looking for source files.
 exclude_patterns = [
     "_build",
+    "**/.nox/**/*",
     "samples/AUTHORING_GUIDE.md",
     "samples/CONTRIBUTING.md",
     "samples/snippets/README.rst",
diff --git a/samples/geography/noxfile.py b/samples/geography/noxfile.py
index 7dbea0914..b008613f0 100644
--- a/samples/geography/noxfile.py
+++ b/samples/geography/noxfile.py
@@ -39,7 +39,7 @@
 
 TEST_CONFIG = {
     # You can opt out from the test for specific Python versions.
-    "ignored_versions": ["2.7"],
+    "ignored_versions": [],
     # Old samples are opted out of enforcing Python type hints
     # All new samples should feature them
     "enforce_type_hints": False,
@@ -86,8 +86,8 @@ def get_pytest_env_vars() -> Dict[str, str]:
 
 
 # DO NOT EDIT - automatically generated.
-# All versions used to tested samples.
-ALL_VERSIONS = ["2.7", "3.6", "3.7", "3.8", "3.9"]
+# All versions used to test samples.
+ALL_VERSIONS = ["3.6", "3.7", "3.8", "3.9"]
 
 # Any default versions that should be ignored.
 IGNORED_VERSIONS = TEST_CONFIG["ignored_versions"]
diff --git a/samples/snippets/noxfile.py b/samples/snippets/noxfile.py
index 7dbea0914..b008613f0 100644
--- a/samples/snippets/noxfile.py
+++ b/samples/snippets/noxfile.py
@@ -39,7 +39,7 @@
 
 TEST_CONFIG = {
     # You can opt out from the test for specific Python versions.
-    "ignored_versions": ["2.7"],
+    "ignored_versions": [],
     # Old samples are opted out of enforcing Python type hints
     # All new samples should feature them
     "enforce_type_hints": False,
@@ -86,8 +86,8 @@ def get_pytest_env_vars() -> Dict[str, str]:
 
 
 # DO NOT EDIT - automatically generated.
-# All versions used to tested samples.
-ALL_VERSIONS = ["2.7", "3.6", "3.7", "3.8", "3.9"]
+# All versions used to test samples.
+ALL_VERSIONS = ["3.6", "3.7", "3.8", "3.9"]
 
 # Any default versions that should be ignored.
 IGNORED_VERSIONS = TEST_CONFIG["ignored_versions"]
diff --git a/scripts/readme-gen/templates/install_deps.tmpl.rst b/scripts/readme-gen/templates/install_deps.tmpl.rst
index a0406dba8..275d64989 100644
--- a/scripts/readme-gen/templates/install_deps.tmpl.rst
+++ b/scripts/readme-gen/templates/install_deps.tmpl.rst
@@ -12,7 +12,7 @@ Install Dependencies
    .. _Python Development Environment Setup Guide:
        https://cloud.google.com/python/setup
 
-#. Create a virtualenv. Samples are compatible with Python 2.7 and 3.4+.
+#. Create a virtualenv. Samples are compatible with Python 3.6+.
 
     .. code-block:: bash